Terrain, alimentation & COVID 19

2. Le surpoids & COVID 19

3. Les prédispositions dans les pathologies médiquées

4. Les prédispositions hépatiques

Bibliographie sur le coronavirus

Bibliographie sur les maladies modernes

Préambule

Comme l’indique la médecine Āyurvédique ainsi que de de nombreux chercheurs contemporains la contamination par le virus COVID 19 dépend du système immunitaire et du terrain (voir l’article Renforcer son Immunitaire en Urgence) lui-même sous l’influence directe de l’alimentation et son pouvoir épigénétique.

Néanmoins de nombreuses autres évidences scientifiques montrent la relation entre alimentation avec force de résistance versus vulnérabilité au coronavirus.

1. Les 5 terrains pathologiques favorables du COVID 19

Selon les chiffres de l’OMS le virus et sa virulence s’adressent de préférence aux individus souffrants des 5 pathologies principales nommées par l’OMS maladies préventibles non-communicables ou maladies de style de vie (preventable non-communicable diseases ou life style diseases).

Produiced by National Institute of Health & WHO (World Health Organisation) in 1999

Taux de mortalité du COVID-19 associé aux 5 maladies préventibles (MNT)
Pathologies préexistantes	Taux de mortalité (Case Fatality Rate-CFR)*	Taux de mortalité incluant tous les cas**
Maladies cardio-vasculaires	13.2%	10.5%
Diabètes	9.2%	7.3%
Maladies respiratoires chroniques	8.0%	6.3%
Hypertension	8.4%	6.0%
Cancer	7.6%	5.6%
Total	46.40%	35.70%
N’ayant pas d’antécédent pathologique connu		0.9%

* Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19) . (2020).

** The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) — China, 2020 - The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team. (2020).

Dans une étude comprenons 1099 patients attends du COVID 19 confirmé en laboratoire, 261 (23.7%) ont déclaré avoir au moins une comorbidité parmi les maladies modernes incluant l'hypertension, le diabète et les maladies coronariennes. (Cf. Mao, R., Liang, J., Shen, J., Ghosh, S., Zhu, L.-R., Yang, H., … Chen, M.-H. (2020)).

Le terme de maladie cardiovasculaire est souvent également remplacé par le terme de maladies du cœur, maladies pulmonaires s’additionnent fréquemment d’asthme.

(Cf. People who are at higher risk for severe illness | CDC. (n.d.). Retrieved March 29, 2020, from Centres for Disease Control and Prevention and OMS)

2. Le surpoids & COVID 19

Le surpoids (IMC supérieur à 20) est une maladie éminemment moderne préventible et elle est aussi selon le CDC (Centers for Disease Control and Prevention) un facteur favorisant prédominant pour le COVID 19.

Le surpoids est connu pour son corollaire morbide de cancers, maladies coronariennes, diabètes, accidents vasculaires cérébraux & mortalité précoce.

Le surpoids ajouté à ces maladies associées représente une double menace favorisant l’infection et les conséquences létales du coronavirus.

(Cf. People who are at higher risk for severe illness | CDC. (n.d.). Retrieved March 29, 2020, from Centre for Disease Control and Prevention.

3. Les prédispositions dans les pathologies médiquées

Les corticoïdes et d'autres médicaments affaiblissent le système immunitaire et rendent vulnérable au COVID 19.

Ces médicaments sont les traitements de prédilection des maladies modernes non-transmissibles telles que maladies inflammatoires, auto-immunes, rhumatoïdes.

(Cf. People who are at higher risk for severe illness | CDC. (n.d.). Retrieved March 29, 2020, from Centre for Disease Control and Prevention)

4. Les prédispositions hépatiques

Plusieurs études ainsi que le CDC (Centers for Diseases Control) ont démontré d’étonnantes corrélations entre le terrain favorable au COVID 19 et la fragilité du foie.

Une étude a montré selon les régions jusqu’à 53.1 % des patients ayant une fonction hépatique anormale et 11 % une pathologie du foie.

(Cf. Zhang, C., Shi, L., & Wang, F. (2020). Liver injury in COVID-19: management and challenges. The Lancet, 10(20)

- Cf. People who are at higher risk for severe illness | CDC. (n.d.). Retrieved March 29, 2020, from Centre for Disease Control and Prevention)

Les patients qui étaient qualifiés comme ayant une anomalie de la fonction hépatique étaient par exemple ceux dont les analyses de sang indiquaient les élévations des marqueurs hépatique comme ASAT, ALAT, bilirubine, etc.

(« Abnormal liver function tests, including elevated ASAT (aspartate aminotransferase), ALAT (alanine aminotransferase), and total bilirubin were noted » Cf. Guan, W.-J., Ni, Z.-Y., Hu, Y., Liang, W.-H., Ou, C.-Q., He, J.-X., …(2020))

Bibliographie sur le coronavirus

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Zhang, C., Shi, L., & Wang, F. (2020). Liver injury in COVID-19 : management and challenges. The Lancet, 10(20), 2019–2021. https://doi.org/10.1016/S2468-1253(20)30057-1

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Les 5 (+1) maladies modernes les plus meurtrières (71 % de la cause totale des décès mondiaux) en augmentation	Les 6 maladies prédisposant à une atteinte morbide du COVID 19
Cancers	Cancers
Maladies cardio-vasculaires incluant hypertension	Maladies cardio-vasculaires
Maladies cardio-vasculaires incluant hypertension	hypertension
Diabètes	Diabètes
Maladies respiratoires chroniques	Maladies respiratoires chroniques
Insuffisances rénales chroniques	Insuffisances rénales chroniques
Cette dernière pathologie n’est pas toujours incluse dans la liste réduisant à 4 (+1) & 5 les deux listes

Obésité mondiale en 2016
39 %	Population d’adultes (plus de 18 ans)	France juste derrière les États-Unis
18 %	Population d’enfants (moins de 18 ans)	France dans la même tranche que les États-Unis
Obésité États-Unis en 2030 prévisionnel
75 %	75 % obèse (IMC supérieur ou égal à 25) = 50 % obésité moyenne (IMC supérieur ou égal à 30) + 25 % obésité sévère (IMC supérieur ou égal à 40)
Obésité = IMC supérieur ou égal à 30 (Cf Ourworldindata, OMS, etc.)

Proportion de la population aux USA souffrant ou qui souffrira de surpoids ou d’obésité		Sources
2015-2016	71.6 % des adultes souffrent de surpoids (IMC supérieur à 25).	CDC (https://www.cdc.gov/nchs/fastats/obesity-overweight.htm)
2019	40% obèses (IMC supérieur ou égal à 30) 18% obèses (IMC supérieur ou égal à 35).	Close to half of U.S. population projected to have obesity by 2030". Harvard Gazette. December 18, 2019. Retrieved March 13, 2020.
2020	75 % surpoids
2030	75 % obèse (IMC supérieur ou égal à 25) = 50 % obésité moyenne (IMC supérieur ou égal à 30) + 25 % obésité sévère (IMC supérieur ou égal à 40).

Antécédent médical des patients touché par le Covid 19
Anomalies de la fonction hépatique	Jusqu’à 53.1 %
Pathologie hépatique	Jusqu’à 11 %

Terrain, alimentation & COVID 19